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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MERTK
All Species:
19.39
Human Site:
S973
Identified Species:
47.41
UniProt:
Q12866
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12866
NP_006334.2
999
110249
S973
G
V
S
W
S
H
S
S
M
L
P
L
G
S
S
Chimpanzee
Pan troglodytes
XP_515690
1233
133559
S1207
G
V
S
W
S
H
S
S
M
L
P
L
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001086951
1001
110501
S975
G
V
P
W
S
H
S
S
T
L
P
L
G
S
S
Dog
Lupus familis
XP_540175
1028
113128
S1002
G
V
S
W
S
Q
S
S
T
L
P
L
G
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60805
994
110139
S968
G
V
S
W
S
H
H
S
T
L
P
L
G
S
P
Rat
Rattus norvegicus
P57097
994
109405
S968
G
I
S
W
S
H
H
S
T
L
P
L
G
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519173
260
28358
M235
S
Q
R
V
P
K
P
M
V
I
L
P
F
M
K
Chicken
Gallus gallus
Q98949
873
96384
E848
L
G
D
D
V
E
G
E
R
H
P
E
G
Q
E
Frog
Xenopus laevis
Q8QFP9
880
97916
E855
S
S
S
A
Q
N
G
E
A
R
G
L
L
H
E
Zebra Danio
Brachydanio rerio
Q9YI66
874
97580
D849
G
P
S
V
S
A
I
D
E
E
S
R
H
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
95.5
82
N.A.
81.1
80.5
N.A.
21.8
37.9
37.3
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.6
97.1
87.3
N.A.
87.7
88.4
N.A.
23.7
55
54.1
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
80
73.3
N.A.
0
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
80
N.A.
80
80
N.A.
13.3
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
20
10
10
0
10
0
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
70
10
0
0
0
0
20
0
0
0
10
0
70
0
0
% G
% His:
0
0
0
0
0
50
20
0
0
10
0
0
10
10
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
60
10
70
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
20
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
10
0
10
0
0
0
70
10
0
0
30
% P
% Gln:
0
10
0
0
10
10
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
10
10
0
10
0
0
0
% R
% Ser:
20
10
70
0
70
0
40
60
0
0
10
0
0
70
30
% S
% Thr:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% T
% Val:
0
50
0
20
10
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _